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Randomized Controlled Trial of Zonisamide for the Treatment of Refractory Partial-onset Seizures Neurol 57:1774-1779, Faught,E.,et al, 2001 See this aricle in Pubmed Article Abstract Zonisamide is effective and well tolerated as an adjunctive agent for refractory partial-onset seizures. The minimal effective dosage was 100 mg/d, but 400 mg/d was the most effective dosage.

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